Organizational part - 5 minutes
Rollcall of the students and elucidation the reasons of the absence of students, checking of the conspectus. Number of forming competencies:knowledge, practical skills. Main questions of the theme: 45 minutes 1. General concepts about biological membranes. 2. Modern concepts about the structure of membrane. 3. Model of Davson and Danielli, mosaic model, liquid-crystal model and etc. 4. Main functions of biological membranes. 5. Types and functions of membrane proteins. 6. Phasic transitions. Break - 10 minutes Learning and teaching methods: - analysis and discussing of main and control questions; - solving of standard and situational problems; - testing. Methods of the control of formed at classes competencies: - solving of standard and situational problems; - opinions exchanging at the studying of educational material; - testing on a computer (a student has to give the answers for test questions that contain minimal knowledge and skills – main definitions, theoretical questions of the theme). Students’ independent work - 30 minutes · Explain the context and find the ways of solving the problems. · Transform the formula and convert the unit of physical quantities. Problems: 1. Calculate the time 2. Calculate the root mean square displacement of protein molecules in 2 sec if the coefficient of lateral diffusion for them is approximately 10-12 mm2/sec. 3. How will the electrical (specific) capacity of membrane change at its transition from liquid-crystal state to the gel if it is known that in liquid-crystal state the thickness of hydrophobic layer is 3,9 nm and in the state of gel it is 4,7 nm. Permittivity of lipids» 2. 4. Calculate the permittivity of membrane lipids if the thickness of membrane is d=10 nm, specific capacitance is С=1,7 mF/m2. 5. At the phasic transition of membrane phospholipids from liquid-crystal state to the gel the thickness of bilayer changes. How will the capacitance of membrane change? How will the electrical field strength change in membrane?
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of sedentary life and the frequency of hoppings 
from one membrane layer to another one of the lipids of sarcoplasmic reticulum membrane if the coefficient of lateral diffusion is D=45 µm2/sec and the area of one phospholipid molecule is А=1,9 nm2.
